2020. 2. 14. 12:06ㆍ카테고리 없음
.AbstractThe effectiveness of vaccines for the prevention and control of human diseases is becoming increasingly recognised. Furthermore vaccines have a high safety margin. The benefits offered by a vaccine to society are enormous, particularly if the disease against which it protects has a high incidence, is usually severe, or has a significant case fatality rate. Moreover, prevention of diseases through vaccination has been shown to be extremely beneficial, not only in reducing disease morbidity, mortality and human suffering, but also in diminishing direct and indirect healthcare costs.
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A United Nations Children’s Fund (UNICEF) study has shown that there is an inverse correlation between the under-5 mortality rate and vaccine coverage of a population (UN Children’s Fund, 1989). For these reasons interest in the development of new vaccines and improvement of existing ones is growing rapidly around the globe. In the past three decades, the number of diseases which can be prevented by vaccination has increased considerably, from 15 in 1960 to 33 in 1990 (Nat. Allergy and Infectious Diseases, 1992).
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